September 2012

Conference Paper

Dual-headed SPECT for awake animal brain imaging

By:
Lee, Seung; Weisenberger, A; McKisson, J; Goddard Jr, James S; Baba, Justin S; Smith, M
Page Number:
3250-3252
Volume:
N/A
Publication Date:
September 12, 2012
Conference Name:
2011 IEEE Nuclear Science Symposium and Medical Imaging Conference
Conference Location:
Valencia, Spain
Conference Sponsor:
IEEE

Abstract

Abstract- Motion-corrected awake animal imaging is needed for normal-state investigations of models of neurological disease and brain activity. The awake animal brain SPECT/CT system, AwakeSPECT at Johns Hopkins University has in the past used a single gamma camera for imaging. Enhancements have been made by adding a pinhole collimator to the second gamma camera at the opposite side which has been previously equipped parallel hole collimator. Geometry calibration was performed using a custom built quality control phantom containing three Co-57 point sources and applied to the tomographic reconstruction code. Hot-rod phantom scans with Tc-99m were performed to test sensitivity and resolution improvements. The reconstruction results show significant resolution and sensitivity improvements.